COMPARISON OF A MEDITERRANEAN (Med) DIET
TO LOW FAT (LF) DIET ON LIPIDS IN PATIENTS (pts) WITH CORONARY HEART DISEASE
(CHD). D Colquhoun, P Glasziou,P Horsley*, S Somerset, B
Gallagher, J Weyers. Core Research Group1, University of
Queensland2, The Wesley Hospital3, Griffith University4,
Brisbane, Australia for OLIVE Group Objective: To compare LF to Med diet
effects on lipids and major lipoproteins in pts with CHD on statin therapy. Method: 68 pts with CHD documented by coronary angiography
were randomised to LF (20-25% energy (E) from fat and 8-10% saturated) or Med
(35-40% E from fat and >50% of fat being monounsaturated). Lipids were
measured prior to lipid lowering drug therapy, at randomisation (x2) and 3mths
(x2). Results: At randomisation and 3mths 86%pts LF
and 80% pts Med were on statins. Similarly, 80% LF and 85% Med pts were taking
aspirin. LF
(n=34) Med
(n=34) Wk
0 3 mths Wk
0 3 mths Cholesterol Triglycides HDL-C LDL-C 6.59 2.81 1.18 3.92 4.48
4.44 1.59
1.63 1.11
1.17 2.61
2.51 4.43
4.34 1.48
1.38 1.17
1.2 2.58
2.46 Conclusion: A
Med diet is as efficacious for lipid management as a LF diet in pts with CHD on
statin therapy. Current dietary recommendations for CHD could consider a Med
diet as a treatment and preventative dietary option. This would extend choice
for pts and possibly enhance adherence.
Pre
Statin (LF & Med)
