CSANZ Daily Highlights Session at ESC Congress | 27 August

CSANZ will be presenting a Daily Highlights session at the ESC Congress on Saturday, 27 August. The session will be hosted by Stephen Nicholls, Will Parsonage, Julie Redfern and Elizabeth Paratz.

If you are in Barcelona, you can attend the session at the Global Stage in the Global Community area at 10.15am.

For those of us back home in Australia and New Zealand, the session will be available to watch online on the Global Community dedicated section of the ESC Congress platform.

Complimentary restricted access to ESC Congress 2022

The restrictive access will enable you to enter these areas on the congress digital platform:

Research Gateway – abstracts and clinical cases. Comment, share and like on your favourites. Open from 22 August with all the Moderated ePosters, complemented with oral abstracts and clinical cases after the sessions and until 12 September.

Global Community – connect with your National Cardiac Society to network, discuss the science in a local context, and catch up with colleagues. Open from 22 August to 12 September.

Click this link to get your complimentary restricted access.

For full access to ESC Congress, registration is required as usual. Click here.

Congratulations to the 2022 CSANZ ASM Ralph Reader Prize winners

2022 Ralph Reader Prize in Basic and Translational Science

Winner:  Dinesh Selvakumar, Westmead Institute for Medical Research

Abstract:  Cellular Heterogeneity in Human Pluripotent Stem Cell Derived Cardiomyocyte Grafts are responsible for Arrhythmias and are Treatable with Pharmacotherapy and Catheter Ablation

Read article in full here as published in the Heart Lung and Circulation Journal.

Judges: Jonathan Kalman, Louise Burrell, Rebecca Ritchie and Len Kritharides

2022 Ralph Reader Prize in Clinical Science

Winner:  Julia Isbister, Centenary Institute
Abstract: Cellular Heterogeneity in Human Pluripotent Stem Cell Derived Cardiomyocyte Grafts are Responsible for Arrhythmias and are Treatable with Pharmacotherapy and Catheter Ablation


Read article in full here as published in the Heart Lung and Circulation Journal.

Judges: Ralph Stewart, Derek Chew, Gemma Figtree, Julie Redfern

2022 CSANZ ASM Prize winners

Congratulations to all the 2022 ASM Prize Winners

Allied Health, Science and Technology Prize
Winner:  Adam Livori, Ballarat Health Services

Assessment of Telehealth Cardiology Pharmacist Clinic in Improving Therapy Adherence following Acute Coronary Syndrome and PCI.
 
Read abstract in full as published in Heart Lung and Circulation Journal.

Judges: Judith Katzenellenbogen, Andrew Maiorana, Katrina Poppe

Cardiac Imaging Prize
Winner:  Aaisha Ferkh, Westmead Hospital

Echocardiographic deep phenotyping of hypertrophic cardiomyopathies: amyloid, Anderson-Fabry and hypertensive heart disease.
Read abstract in full as published in Heart Lung and Circulation Journal.

Judges: Selwyn Wong, Raj Puranik, Rebecca Kozor

Cardiovascular Nursing Prize
Winner:  Kristel Janssens, Baker Heart and Diabetes Institute

Modest association between peak exercise blood pressure and ambulatory hypertension in endurance athletes.
Read abstract in full as published in Heart Lung and Circulation Journal.

Judges: Patricia Davidson, Kimberley Bardsley, Christopher Lee

Heart Failure Prize
Winner:  David Chieng, Baker Heart and Diabetes Institute

Catheter ablation in atrial fibrillation and heart failure with preserved ejection fraction improves peak pulmonary capillary wedge pressure, exercise capacity and quality of life. A Prospective Randomised Controlled Trial (RCT-STALL HFpEF).
Read abstract in full as published in Heart Lung and Circulation Journal.

Judges: Andrew Sindone, Rob Doughty, Theresa McDonagh

Heart Rhythm Prize
Winner:  Ahmed Al-Kaisey, Royal Melbourne Hospital

Polygenic risk scores identify atrial electrophysiological substrate abnormalities and predict atrial fibrillation recurrence following catheter ablation.
Read abstract in full as published in Heart Lung and Circulation Journal.

Judges: Andrew Martin, Livia Hool, Karen Phillips

Indigenous Health Prize
Winner:  Keriana Kingi-Nepe, Gisborne Hospital NZ

The impact of Sacubitril-Valsartan on Te Tairāwhiti (Gisborne and East Coast) region.
Read abstract in full as published in Heart Lung and Circulation Journal.

Judges: Alex Brown, Karen Brewer

Paediatric and Congenital Cardiology Prize
Winner:  Elizabeth Paratz, Baker Heart and Diabetes Institute

Prevalence of coronary artery anomalies in young sudden cardiac death: insights from a prospective state-wide registry.
Read abstract in full as published in Heart Lung and Circulation Journal.

Judges: Clare O’Donnell, Mugur Nicolae

Prevention Prize
Winner:  Louise Segan, Baker Heart and Diabetes Institute

Development and validation of the HARMS2-AF lifestyle risk score to predict incident AF.
Read abstract in full as published in Heart Lung and Circulation Journal.

Judges: David Colquhoun, Julie Redfern, Robyn Gallagher

2022 CSANZ ASM New Investigator Poster Prizes

Medical Student Poster Prize
Winner:  Angus Fung, UNSW

Title: Prognostic association supports indexing size measures in echocardiography by body surface area.

Judges: Peter Psaltis and Dominica Zentner

Basic Physician Trainee or Advanced Trainee Poster Prize 
Winner:  Gavin Huangfu, Fiona Stanley Hospital

Title:  CT evaluation of hepatic fat: A novel marker for high-risk coronary atherosclerosis in Familial Hypercholesterolaemia.

Judges: Matthew Worthley, Liza Thomas

PhD Candidate Poster Prize 
Winner: Himawan Fernando, Alfred Health

Title: LidocAine Versus Opioids In MyocarDial infarction: The AVOID-2 randomised controlled trial.

Judges: Clara Chow, Will Parsonage

Cardiovascular Nursing Poster Prize 
Winner:  Nathan Herbert, Barwon Health

Title: Impact of COVID-19 pandemic lockdown on a Victorian regional ST-elevation myocardial infarction service.

Judges: Caleb Ferguson, Rochelle Wynne 

Allied Health, Science and Technology Poster Prize
Winner:  Clara Zwack, University of Sydney

Stress and its relationship to cardiovascular risk in young adults with intellectual disability

Judges: Lee Nedkoff, Stacey Nielson

Congratulations to all finalists in the prize sessions and thank you to all the judges.

2022 RT Hall Prize winner at CSANZ ASM – Prof Gerald Watts

The RT Hall Prize is the most prestigious research award of CSANZ and recognises the achievements of senior and established investigators.
The 2022 R T Hall Prize is awarded to Prof Gerald Watts.

Professor Watts is the Winthrop Professor of Cardiometabolic and Internal Medicine at the University of Western Australia and Senior Consultant Physician at the Royal Perth Hospital.

Over the course of the last 25 years he has established a globally recognised translational research program in Perth, which has extended his fundamental interest in dyslipidaemia and diabetes to developing world class models in health service delivery. He published the seminal paper outlining the importance of lipid lowering in the regression of angiographic disease in an era prior to the use of more advanced arterial wall imaging. His work has enabled a fundamental understanding of the clinical and pharmacological factors that influence lipoprotein metabolism and he has played a pivotal role in the early development of a number of novel therapies that target cardiometabolic risk. In recent years, he has led national efforts to develop effective, multidisciplinary clinical models of care for familial hypercholesterolaemia and associated research and training initiatives. 

The role of Street Side Medics for Australians experiencing homelessness

Cardiovascular disease in the Australians experiencing homelessness, and the role of Street Side Medics

 

“The enjoyment of the highest attainable standard of health is one of the fundamental rights of every human being without distinction of race, religion, political belief, economic or social condition”.

     –  World Health Organisation

Over 100 million people are experiencing homelessness globally, with an estimated 1.6 billion living under inadequate shelter. As of the 2016 Census, there were 116, 427 Australians characterised as homeless(1). Whilst this figure represents less than 1% of Australia’s total population, people experiencing homelessness are over-represented in health statistics, particularly in relation to cardiovascular disease.

Status of CVD in homeless Australians

Cardiovascular disease (CVD) affects 17% of all Australians(2), and is the leading cause of mortality, accounting for a quarter of all deaths in 2019(3). Compared to the general population, CVD amongst those experiencing homelessness has a higher prevalence and mortality, as well as a greater burden of contributing risk factors, and an earlier age of onset (4-6). Whilst Australian data is scarce, international studies have shown a similar or slightly higher prevalence of hypertension, diabetes, and dyslipidaemia in those experiencing homelessness (7-10), and these statistics do not account for the likely under-diagnosis of these conditions. Substance use, particularly tobacco, is significantly more prevalent, with local data demonstrating that up to 81% (11, 12) of those who experience homelessness smoke cigarettes, compared to 15% of the general Australian population(13). Alcohol dependence, as well as cocaine and methamphetamine usage, all of which are detrimental to long-term cardiac health, are more prevalent in the Australian homeless population (14). Similarly, mental health disorders are three times more likely in the homeless population(15), and these have also been linked to poorer cardiovascular outcomes(16), reduced engagement with health services(17) and lower medication adherence(18).

There are various obstacles to delivering healthcare to Australians experiencing homelessness, which can be categorised into personal, practical and relationship barriers (19). Personal barriers refer to competing priorities such as shelter and food instead of medicine or appointments, which lead to many homeless Australians only seeking medical attention in perceived emergencies. Practical barriers refer to the concrete obstacles of finances, transport, and medication security. Finally, relationship barriers encompass the stigmatisation and lack of trust in the healthcare system, arising from prior negative experiences or perceived clinician bias(20).

The role of Street Side Medics

Accessible, opportunistic, and tailored care is essential. Tackling the increased burden of CVD in Australia’s homeless population requires focus on primary and secondary prevention, but also the development of pragmatic interventions which consider and address the underlying social determinants.

One promising strategy is through “drop-in” outreach clinics which make healthcare considerably more accessible. This was the vision of Dr. Daniel Nour, who founded Street Side Medics in August 2020, and for which he won Young Australian of the Year in 2022, recognising the early success of the service. Street Side Medics is a drop-in clinic service, operated from a mobile medical van, which delivers targeted healthcare at homeless food services, shelters, temporary accommodations, and disaster-affected zones in New South Wales. It is a bulk-billed, volunteer run GP led service, which does not require Medicare or identification, and utilises modern medicine technology including point of care testing, portable ultrasound, echocardiography, and spirometry, within a custom-built mobile clinic to provide opportunistic access to healthcare. In doing so, the model strives to alleviate the personal, practical and relationship barriers, which those experiencing homelessness face. This initiative has recently received Australian Federal Government funding in 2022(21)to help expand and adequately deliver its primary care service to homeless Australians. Professor Ravi Bhindi, head of department of the Royal North Shore Cardiology Department has also been involved since conception and has recently initiated a research arm of Street Side Medics, aiming to better understand the burden of cardiovascular disease in Australians experiencing homelessness.

To learn more: www.streetsidemedics.com.au/what-we-do

Moving forward, we need continued government proactivity with increased supply of social and affordable housing. Healthcare services must be adaptive and holistic and involve collaboration with the local community. It is imperative that we continue to spread awareness, not only in the medical fraternity, but within all levels of society. We hope to improve the general understanding of the challenges faced by our homeless population, to facilitate constructive conversations towards a more compassionate and caring society.

Dr. Karan Rao

On behalf of Dr. Daniel Brieger, Dr. Daniel Nour, Ms. Alex Baer & Professor Ravinay Bhindi

StreetSide Medics Homeless Health Research Group

References

  1. Australian Bureau of Statistics. Census of Population and housing: Estimating homelessness, 2016. In: Government A, editor. Canberra2018.
  2. Australian Bureau of Statistics. Causes of Death, Australia: ABS Website; 2020 [Available from: https://www.abs.gov.au/statistics/health/causes-death/causes-death-australia/2020#content.
  3. Health AIo, Welfare. Heart, stroke and vascular disease—Australian facts. Canberra: AIHW; 2021.
  4. Flatau P, Lester L, Seivwright A, Teal R, Dobrovic J, Vallesi S, et al. Ending homelessness in Australi: An evidence and policy deep dive. UWA Business School, The University of Western Australia; 2021.
  5. Al-Shakarchi NJ, Evans H, Luchenski SA, Story A, Banerjee A. Cardiovascular disease in homeless versus housed individuals: a systematic review of observational and interventional studies. Heart. 2020;106(19):1483-8.
  6. Nanjo A, Evans H, Direk K, Hayward AC, Story A, Banerjee A. Prevalence, incidence, and outcomes across cardiovascular diseases in homeless individuals using national linked electronic health records. Eur Heart J. 2020;41(41):4011-20.
  7. Bernstein RS, Meurer LN, Plumb EJ, Jackson JL. Diabetes and hypertension prevalence in homeless adults in the United States: a systematic review and meta-analysis. Am J Public Health. 2015;105(2):e46-60.
  8. Lee TC, Hanlon JG, Ben-David J, Booth GL, Cantor WJ, Connelly PW, et al. Risk factors for cardiovascular disease in homeless adults. Circulation. 2005;111(20):2629-35.
  9. Scott J, Gavin J, Egan AM, Avalos G, Dennedy MC, Bell M, et al. The prevalence of diabetes, pre-diabetes and the metabolic syndrome in an Irish regional homeless population. Qjm. 2013;106(6):547-53.
  10. Kim DH, Daskalakis C, Plumb JD, Adams S, Brawer R, Orr N, et al. Modifiable cardiovascular risk factors among individuals in low socioeconomic communities and homeless shelters. Fam Community Health. 2008;31(4):269-80.
  11. Nielssen O, Chudleigh A, Chen M, Large M, Markovic T, Cooper L. Results of a metabolic health clinic at a hostel for homeless men. Australas Psychiatry. 2017;25(3):270-3.
  12. Kermode M, Crofts N, Miller P, Speed B, Streeton J. Health indicators and risks among people experiencing homelessness in Melbourne, 1995-1996. Aust N Z J Public Health. 1998;22(4):464-70.
  13. Greenhalgh EM BM, Scollo MM. 1.3 Prevalence of smoking – adults Melbourne: Cancer Council Victoria; 2021 [updated December 2021. Available from: http://www.tobaccoinaustralia.org.au/chapter-1-prevalence/1-3-prevalence-of-smoking-adults.
  14. Scutella R, Tseng Y-P, Wooden M. Journeys Home: Tracking the most vulnerable. 2017. 2017;8(3):17.
  15. Health AIo, Welfare. Mental health services in Australia. Canberra: AIHW; 2022.
  16. Correll CU, Solmi M, Veronese N, Bortolato B, Rosson S, Santonastaso P, et al. Prevalence, incidence and mortality from cardiovascular disease in patients with pooled and specific severe mental illness: a large-scale meta-analysis of 3,211,768 patients and 113,383,368 controls. World Psychiatry. 2017;16(2):163-80.
  17. Resurrección DM, Moreno-Peral P, Gómez-Herranz M, Rubio-Valera M, Pastor L, Caldas de Almeida JM, et al. Factors associated with non-participation in and dropout from cardiac rehabilitation programmes: a systematic review of prospective cohort studies. European Journal of Cardiovascular Nursing. 2019;18(1):38-47.
  18. Kronish IM, Rieckmann N, Halm EA, Shimbo D, Vorchheimer D, Haas DC, et al. Persistent depression affects adherence to secondary prevention behaviors after acute coronary syndromes. J Gen Intern Med. 2006;21(11):1178-83.
  19. Davies A, Wood LJ. Homeless health care: meeting the challenges of providing primary care. Med J Aust. 2018;209(5):230-4.
  20. Gilmer C, Buccieri K. Homeless Patients Associate Clinician Bias With Suboptimal Care for Mental Illness, Addictions, and Chronic Pain. J Prim Care Community Health. 2020;11:2150132720910289.
  21. Commonwealth of Australia. Budget 2022-2023. Canberra; 2022 March 29, 2022.

Launch of the Australian Stroke and Heart Research Accelerator (ASHRA)

Thursday 11 August from 5:15pm
CSANZ ASM • Gold Coast Convention and Exhibition Centre • Room 5 (Level 1)

Join us at the CSANZ meeting on the Gold Coast to officially launch the Australian Stroke and Heart Research Accelerator (ASHRA), funded by the MTPConnect Targeted Translation Research Accelerator (TTRA) program.

Come along and learn about the Centre, some of the early research we are funding, and how you can get involved. We can’t wait to share the exciting details of this collaborative, national centre with the CSANZ community.

Download Program_Launch ASHRA

Abbott: Subset of Assurity™, Endurity™ and Zenex™ Pacemakers (July 2022)

A laser surface preparation may not have properly prepared the device’s metal housing potentially leading to abnormal device-to-header adhesion which may allow moisture ingress into the header. 

ANZCDACC Product Hazard Alert July 2022

  Download as pdf

Device:   A subset of Assurity™, Endurity™ and Zenex™ Pacemakers
MODELS:  PM2162, PM2172, PM2272, PM2282*
* TGA Approved but not currently commercially released
TGA Reference: 
RC-2022-RN-01000-1

Congratulations to our Ralph Reader Finalists in Basic and Translational Science

GOOD LUCK to all our passionate #CSANZ2022 Ralph Reader Prize Finalists presenting in Basic and Translational Science on Friday morning directly after the Opening and R T Hall Lecture.

Miss Connie Jiang presenting: A calibrated functional patch clamp assay to enhance clinical variant interpretation in KCNH2-related long QT syndrome – Victor Chang Cardiac Research Institute
Dr Dinesh Selvakumar presenting: Cellular Heterogeneity of Pluripotent Stem Cell Derived Cardiomyocyte Grafts is Mechanistically Linked to Treatable Arrhythmias – The Westmead Institute for Medical Research
Ms Khalia Primer presenting: Diabetes impairs endothelial cell metabolic reprogramming and angiogenic responses to hypoxia, which are rescued by reconstituted high-density lipoproteins (rHDL)  – SAHMRI

Friday 12 August is going to be a big day with a full program of fascinating presentations by experts and young inspiring researchers… and in the evening join the fun Poster Presentations with wine and cheese (from 5.45pm).

Meet all the Young Investigators with Posters on display and discuss their work – it’s a great time for networking.

Register Now!

Congratulations to our Ralph Reader Finalists in Clinical Science

Congratulations to all our CSANZ 2022 Ralph Reader Prize Finalists in Clinical Science.

  • Dr Alexandra Murphy presenting: SMARTphone-based cardiovascular risk reduction in BREAST cancer patients [SMART-BREAST]: A randomized controlled trial Austin Health
  • Dr Jonathan Ariyaratnam presenting: Invasive Haemodynamic Testing with Fluid Challenge to Explore the Relationship Between Heart Failure with Preserved Ejection Fraction in Atrial Fibrillation The University of Adelaide
  • Dr Julia Isbister presenting: “Concealed cardiomyopathy” is an important cause of autopsy-inconclusive sudden cardiac death and diagnosis impacts care of surviving relatives. Centenary Institute

See the program here

We look forward to seeing your amazing presentations on Saturday morning on 13 August 2022 at the #CSANZ2022 on the Gold Coast.

The CSANZ Prize Ceremony will be held after lunch on Saturday 13 August 2022.

Good Luck to all!

 

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