Heart Failure Research Review, Issue 71, with commentary by Dr Mark Nolan

In this issue:

  • Dapagliflozin in HF with mildly reduced or preserved EF
  • Acetazolamide in acute decompensated HF with volume overload
  • Association of empagliflozin treatment with albuminuria in HF patients
  • Hyperkalaemia as a cause of MRA undertreatment in HF
  • Riociguat for pulmonary hypertension with HFPEF
  • Transvenous right greater splanchnic nerve ablation in HFPEF
  • Stem cell-derived extracellular vesicles reduce expression of cardiac hypertrophy molecules
  • Periodontal status, CRP, NT- proBNP and incident HF
  • Alerting clinicians to 1-year mortality risk in patients hospitalised with HF
  • Uric acid and SGLT-2 inhibition with empagliflozin in HFREF

Download the Heart Failure Research Review Issue 71

Longitudinal Assessment of Structural Phenotype in Brugada Syndrome Using CMR

Longitudinal Assessment of Structural Phenotype in Brugada Syndrome Using Cardiac Magnetic Resonance Imaging

Recently published in Heart Rhythm O2 October 17, 2022  

With summary by author, Dr Julia C. Isbister 

Brugada syndrome (BrS) has traditionally been considered a channelopathy but in recent years, paralleling advancement in imaging techniques, subtle structural changes have been observed in a number BrS cohorts around the world. Cardiac magnetic resonance (CMR)imaging has revealed that patients with BrS have increased right ventricular and right ventricular outflow tract volumes compared to health controls. Focal fibrosis evidence by late gadolinium enhancement (LGE) has also been reported. Indeed, it has been postulated that BrS may be a focal cardiomyopathy rather than a pure ion channel disease.

This pilot study (n=18) represents the first time patients with BrS have been studied longitudinally with CMR and revealed that the myocardial changes can develop or progress over time. Most strikingly 22% of patients developed mid-wall LGE, typically associated with dilated cardiomyopathy, in the absence of other identifiable causes.

This work is hypothesis generating and we hope that the interesting results will prompt other groups around the world to review their patients with BrS to determine if progressive structural changes are observed in other cohorts. Ultimately, correlation of any progression of structural change with arrhythmic events and patient outcomes will be needed to determine the clinical implications of these observations and determine if serial structural assessment may aid risk stratification in BrS.

Isbister, J.C. et al, 2022, ‘Longitudinal Assessment of Structural Phenotype in Brugada Syndrome Using Cardiac Magnetic Resonance Imaging’ Heart Rhythm O2  

DOI: https://doi.org/10.1016/j.hroo.2022.10.004 

Read article in full

 

 

New CSANZ and HLC Appointments

Following the recent resignations of Dr Paul Bridgman as Chair of the Education Committee and Prof Stephen Duffy as Honorary Secretary, CSANZ Members are advised the following appointments to these roles.

Prof Jenny Deague (WA) has been appointed by the Board as Chair of the Education Committee and Dr Mayanna Lund (NZ) has been appointed CSANZ Honorary Secretary.

A/Prof Salvatore Pepe has been appointed in-coming Editor-in-Chief of Heart Lung and Circulation. A/Prof Pepe will take over the role at the conclusion of Prof Robert Denniss’ term at the end of 2023.  Prof Denniss will stay on the Board until the November, 2022 Board meeting and a special ceremony will be held at the 2023 AGM to acknowledge Prof Denniss’ service and achievements as HLC Editor-in-Chief.

ECG of the Month – October 2022

A 57 year-old woman with a loop recorder in-situ for investigation of syncope presents to the emergency department with recurrent dizzy spells. Loop recorder tracings (1 & 2) are shown:

Image 1
Image 2

Visit the CSANZ Forum to discuss or post a question to A/Prof Alex Voskoboinik.

The Answer:

When reviewing any loop recorder / device tracings it is important to establish a symptom-rhythm correlation – this patient did not have any symptoms at the time of the two traces. Trace 1 represents clear artefact with non-physiological signals seen at baseline, then accentuated later in the trace. The true QRS complexes can be seen marching through and can be mapped out. It is important to have a high index of suspicion for ‘spurious’ / artefactual / undersensing for all logged episodes when this degree of artefact is seen. In trace 2 (reported as a long pause), one can appreciate gradual QRS signal attenuation likely related to patient position / movement. In fact, if one zooms in closely, the QRS complexes never disappear but just become low amplitude before gradually increasingly in amplitude. Fortunately this patient did not receive a pacemaker or defibrillator on the basis of these traces!

 

New MBS Items from 1 November 2022

Two new MBS items (11736 and 11737) will be introduced for remote monitoring of cardiac ILR devices. These new services will be remote mirror services of current in rooms service MBS items 11728 and 11731, allowing remote services to be performed.  Refer to the Quick Reference Guide for further details now available on MBS Online.

In addition, 8 eight MBS items for cardiothoracic surgery items 38510, 38513, 38516, 38517, 38555, 38556, 38557 and 38572 will be amended to incentivise the use of advanced techniques and procedures. See full details of these changes on the MBS website.

Claiming Guide for repeat MBS services for stress echo and stress MPS

In response to a number of queries regarding claiming of repeat MBS services for stress echo (item 55143) and stress MPS (items 61349, 61410), the MBS has produced a claiming guide to assist providers.  Link to MBS claiming guide 

Note that there are no changes to the requirements of the services for stress echocardiography and stress MPS, including the qualifying indications, time dependencies or item associations that currently exist.

SURVEY | use of mHealth applications in clinical practice – Cardiovascular Nurses

You are invited to participate in a study being led by the University of Wollongong (UOW) about the use of m-Health applications in clinical practice. The survey is anonymous and takes approximately 10-15 minutes complete.

Wa’ed Shiyab (PhD candidate at UOW) is conducting the survey to examine the use of mHealth applications by nurses for chronic conditions and lifestyle risk factors.

You can access the survey by scanning the QR code or via this link https://redcap.link/mHealthnurse

Study investigators include:  Wa’ed Shiyab (PhD candidate) and Prof Liz Halcomb (Primary Supervisor). Dr Kaye Rolls and A/Prof Caleb Ferguson (Co-Supervisors).

If you have any questions, please contact Mrs Wa’ed Shiyab via email or Prof Liz Halcomb email or phone 4221 3784.

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